GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs732528 | 1 | rs1807019 | chr18:48378106 | MRO | chr18:48321491-48351754:- | -0.24 | -4.34 | 1.79E-5 | Entorhinal cortical thickness |
| BLCA | cis | rs10935120 | 1 | rs1814336 | chr3:134200823 | ANAPC13 | chr3:134196547-134204865:- | 0.51 | 8.15 | 5.2E-15 | Height |
| BLCA | cis | rs10935120 | 1 | rs1814336 | chr3:134200823 | CEP63 | chr3:134204575-134293852:+ | 0.26 | 4.46 | 1.06E-5 | Height |
| BLCA | cis | rs10935120 | 1 | rs1814337 | chr3:134200682 | ANAPC13 | chr3:134196547-134204865:- | 0.49 | 7.78 | 6.88E-14 | Height |
| BLCA | cis | rs10935120 | 1 | rs1814337 | chr3:134200682 | CEP63 | chr3:134204575-134293852:+ | 0.24 | 4.14 | 4.28E-5 | Height |
| BLCA | cis | rs1815787 | 1 | rs1815787 | chr11:116921397 | PCSK7 | chr11:117075789-117102811:- | -0.4 | -5.13 | 4.67E-7 | Subjective well-being |
| BLCA | cis | rs7714584 | 1 | rs1816256 | chr5:150272853 | LOC134466 | chr5:150310000-150326146:- | 0.46 | 5.89 | 8.37E-9 | Crohn's disease |
| BLCA | cis | rs950169 | 1 | rs1818950 | chr15:84722521 | LOC388152 | chr15:84867600-84898920:- | -0.27 | -4.67 | 4.2E-6 | Schizophrenia |
| BLCA | cis | rs9457247 | 1 | rs1819333 | chr6:167373547 | RNASET2 | chr6:167343008-167412795:- | -0.22 | -4.75 | 2.95E-6 | Crohn's disease |
| BLCA | cis | rs7714584 | 1 | rs1820682 | chr5:150262142 | LOC134466 | chr5:150310000-150326146:- | 0.47 | 6.2 | 1.42E-9 | Crohn's disease |
| BLCA | cis | rs1830074 | 1 | rs1830074 | chr7:6718674 | C7orf28B | chr7:6838572-6865861:- | -0.26 | -3.95 | 9.31E-5 | Body mass index |
| BLCA | cis | rs1830074 | 1 | rs1830074 | chr7:6718674 | PMS2CL | chr7:6749757-6793492:+ | -0.32 | -5.09 | 5.65E-7 | Body mass index |
| BLCA | cis | rs10461617 | 1 | rs1833896 | chr5:56097669 | C5orf35 | chr5:56205103-56213010:+ | 0.65 | 9.62 | 8.98E-20 | Type 2 diabetes |
| BLCA | cis | rs950169 | 1 | rs1848093 | chr15:84755527 | LOC388152 | chr15:84867600-84898920:- | -0.26 | -4.61 | 5.56E-6 | Schizophrenia |
| BLCA | cis | rs7655841 | 1 | rs1854774 | chr4:129988405 | C4orf33 | chr4:130014829-130033842:+ | -0.32 | -5.36 | 1.41E-7 | Chronic obstructive pulmonary disease (moderate to severe) |